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Suitable auris-acceptable preservatives for use in a formulation or composition disclosed herein include, but are not limited to benzoic acid, boric acid, p-hydroxybenzoates, benzyl alcohol, lower alkyl alcohols (e.g., ethanol, butanol or the like), quaternary compounds, stabilized chlorine dioxide, mercurials, such as merfen and thimerosal, mixtures of the foregoing and the like

Khavinson, Antioxidant properties of geroprotective peptides of the pineal gland, Archives of Gerontology and Geriatrics, Volume 44, Supplement, 2007, Pages 213-216

C.LeskeS.WellerM.et al (2023)

Epithalon exposure in senescent monkeys was associated with higher evening melatonin and changes in the circadian pattern of cortisol

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The lack of association is in contrast with the overall results reported by another study [17], but consistent with the observation reported by 2 out of the 3 sites in that study